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Figure 7 | BMC Cell Biology

Figure 7

From: Stilbene glycosides are natural product inhibitors of FGF-2-induced angiogenesis

Figure 7

The effect of compounds 1 (AI) and 2 (AII) on BAEC invasion into a Matrigel layer was studied using the chemoinvasion assay described below. Cells (1.7 × 104) were added to the Matrigel coated upper Boyden chamber and the compounds with or without FGF-2 added to the lower chamber. Cell invasion was measured after 24 h and assessed as described below. Values significantly different (p < 0.05) from FGF-2 alone are shown by *. Results are the mean of three experiments. (B) Representative photomicrographs are shown for the effect of compound 1 on BAEC (original magnification × 20). Increased migration was seen with FGF-2 (25 ng/ml; panel II) and this was reduced in the presence of compound 1 (panel IV).

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