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Figure 3 | BMC Cell Biology

Figure 3

From: Mouse lung contains endothelial progenitors with high capacity to form blood and lymphatic vessels

Figure 3

Heterogeneity of mouse EPCs immediately after isolation and EPC subclones are bipotent. A-B) CD31+ BECs surround LECs, which are in the centre of a growing colony and which are Lyve1 positive. BECs are more positive for CD31 than LECs and all LECs specifically express the transcription factor Prox1. C-D) After a single-cell clonogenic assay all cells from two representative subclones (D5 and B3) are positive for CD31, a panendothelial marker. Only cells differentiated into lymph endothelial cells (LECs) are Lyve1 or podoplanin positive. 150-200-fold.

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