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Figure 4 | BMC Cell Biology

Figure 4

From: The role of HIF-1 in up-regulating MICA expression on human renal proximal tubular epithelial cells during hypoxia/reoxygenation

Figure 4

Adenoviral mediated overexpression of HIF-1alpha and HIF-1alphaDELTAODD can up-regulate the surface expression of MICA on HK-2 cells in normoxia. The relative protein expression levels were determined by flow cytometry with a PE conjugated mouse anti-human MICA mAb 96 h after transduction in normoxia. The percentage of cells stained by MICA mAb is shown by the numbers in the top right of each graph. (A) HK-2 transduced with Ad.CMV.HIF-1alphaDELTAODD (B) HK-2 transduced with Ad.CMV.HIF-1alpha (C) HK-2 transduced with Ad.CMV.LacZ (D) HK-2 without transduction (E) Isotype control.

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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