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Figure 8 | BMC Cell Biology

Figure 8

From: Activation of GPR40 attenuates chronic inflammation induced impact on pancreatic β-cells health and function

Figure 8

Schematic representation of mechanisms involved for β-cells apoptosis caused by inflammatory cytokines exposure and its reversal by GPR40 activation. Pointed arrows represent activatory signals and blunted lines represent inhibitory signals. Signals propagated from inflammatory cytokines are shown as normal arrows while signals propagated from GPR40 activation are shown as broken arrows/lines.

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