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Figure 3 | BMC Cell Biology

Figure 3

From: Expression of Cyclins A, E and Topoisomerase II α correlates with centrosome amplification and genomic instability and influences the reliability of cytometric S-phase determination

Figure 3

Flow cytometry and BrdU incorporation DNA histograms of HTB-125 (a), MCF-7 (c), MDA-231 (e) cell lines and two parameter histograms (BrdU incorporation vs. DNA content) of HTB-125 (b), MCF-7 (d) and MDA-231 (f) cell lines. As one can see the S-phases in HTB-125 and MCF-7 are very similar with both methods, but in the unstable aneuploid cell line MDA-231, there is a very substantial difference between the measurements with the two methods.

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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