Figure 10From: Mutations in the IGF-II pathway that confer resistance to lytic reovirus infectionIGF-II increases colony formation of L-cells in soft agar. Forced expression of the rat pro-Igf2 gene (pro-Igf2c) in L-cells increases the number of soft-agar colonies by 4 to 5 fold as compared to the L-cell parent, as shown in this representative photomicrograph at 7 days (10×).Back to article page