The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins

Table 1 Quantitative mutation suppression.

Strain genotype	Plasmid/insert	Mutation frequency^a	Standard deviation	Mutagenesis suppression (% reduction of vector control)
mutM mutY	pTrc99a vector only	9799	± 2848	NA^b
mutM mutY	pTrc99a/OXR1 [21]	773	± 324	* 90
mutM mutY	pTrc99a/NCOA7	0.26	± 0.22	* >99.9
mutM mutY	pTrc99a/OXR2 domain of NCOA7 (657–942)	2635	± 725	* 73
Wild type	pTrc99a vector	0.31	± 0.17	* NA

^aMutation frequency (Mutants/10⁷ viable cells). Data represent the averages of at least 6 independent measurements.
^b Not Applicable.

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