Cx isoform | L (μm) | Number of TTs per mm2/ per 100 cellsc | gT (nS) | siRNA/AF488 permeability (×10−14 cm3/s) |
---|---|---|---|---|
TT/(−)GJ (HeLa wt) | 16.3 ± 0.4 (n = 214) | 51 ± 8/ 9.5 ± 1.3 | 6.0 ± 1.1a (n = 17) | 65 ± 38 (n = 5) |
TT/ Cx36-EGFP | 17.0 ± 0.4 (n = 330) | 79 ± 9*/ 30 ± 7.1* | 0.8 ± 0.2 (n = 16) | – b (n = 5) |
TT/ Cx40-CFP | 15.9 ± 0.5 (n = 126) | 46 ± 6/ 9.7 ± 1.8 | 16.5 ± 2.8 (n = 20) | 4.4 ± 2.0 (n = 6) |
TT/ Cx43-EGFP | 17.0 ± 1.1 (n = 96) | 23 ± 4*/ 4.7 ± 0.7* | 8.8 ± 3.4 (n = 7) | 32 ± 17 (n = 4) |
TT/Cx45 | 14.3 ± 1.0 (n = 68) | 5.7 ± 1.6*/ 1.4 ± 0.3* | 4.1 ± 0.5 (n = 41) | – b (n = 8) |
TT/Cx47 | 15.1 ± 0.5 (n = 112) | 27 ± 3*/ 5.0 ± 0.9* | 3.0 ± 0.6 (n = 15) | 4.3 ± 1.9 (n = 6) |