Fig. 7
From: Spatiotemporal patterns of sortilin and SorCS2 localization during organ development
Sortilin expression in mouth, heart, vascular system and skin. Immunohistofluorescence was performed on sagittal sections (10 μm) of embryos on embryonic day E13.5, E15.5 and E17.5. Sortilin is found in the epithelium of the tongue and palate at E13.5 but is gone by E15.5 (a,b). In the cardiovascular system, sortilin is found in the atria and large veins (d-f) but not in the arteries (c), Finally, sortilin is found moderately expressed in the epidermal layers of the skin most prominently at E15.5 (g-i), Green channel is sortilin, and blue channel is Hoechst nuclear stain. Scale bars = 50 μm. Ar, arteries; At, atria of heart; De, dermis; Ep, epidermis; Mo, mouth cavity; Na, nasal cavity; Pa, epithelium of palate; To, tongue; Ve, veins, Vt, ventricle of heart