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Fig. 1 | BMC Cell Biology

Fig. 1

From: Tanshinone IIA reduces SW837 colorectal cancer cell viability via the promotion of mitochondrial fission by activating JNK-Mff signaling pathways

Fig. 1

Tan IIA dose-dependently induces cell death. a LDH release assay for cell death detection. The relative LDH release was measured in SW837 cells. Different doses of Tan IIA were added into the cell medium for 12 h. b LDH release assay in SW480 cells. c-e TUNEL staining for cell death. The number of TUNEL-positive cells was counted. Tan IIA at 1 μ M and 5 μ M were incubated with SW837 and SW480 cells for 12 h. f-k Western blotting was performed to analyze the protein expression relative to mitochondrial apoptosis. *p < 0.05 vs. control group (cont)

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