Parameter | Affected process | Best-fit value | 95% CIs | |
---|---|---|---|---|
k (MBq− 1 × days− 1) | Initial increase in γ-H2AX levels when irradiation starts | 4.65 × 105 | 3.28 × 105 | 6.60 × 105 |
α (MBq−1) | Decrease in γ-H2AX levels due to death of heavily damaged cells | 0.255 | 0.183 | 0.323 |
r (days−1) | Time-dependent decrease in γ-H2AX levels due to radionuclide excretion, DNA repair, and death of heavily damaged cells | 1.07 × 106 | 7.54 × 105 | 1.52 × 106 |
p (unitless) | 0.153 | 0.146 | 0.159 |