Fig. 2
From: Improved homology modeling of the human & rat EP4 prostanoid receptors
Representative images of rEP4 receptor with PGE2 docked. a Surface representation, highlighting channel between helix 5 and helix 6 (cyan/green surfaces), enabling interaction with molecules within phospholipid bilayer. b Edges of implicit membrane superimposed on cartoon representation of rEP4 receptor. c Desmond MD simulation model featuring explicit membrane. PGE2 shown in in blue with an arrow pointing to the site