Fig. 5From: CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switchesa and b: (a) Two crystallographic CD40 monomers associate to form a tight antiparallel dimer (grey, green) which bind to ABBV-323 Fab (shown in magenta). (b) LCDR1 R32 inserts in the second crystallographic monomer shown in green. R32 makes interactions with backbone carbonyls to A25/S35 and sidechain Q36Back to article page