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Fig. 7 | BMC Molecular and Cell Biology

Fig. 7

From: PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth

Fig. 7

PGRMC1 Y180 contributed to growth of subcutaneous mouse xenograft tumors. a There are no differences in cell doubling time in culture. Replicates of stable cell lines 1–3 for each condition were measure to give n = 6. There were no significant differences between cell conditions. b Typical tumors produced by each respective class of cell. c Box plot of the distribution of tumor sizes among mice injected with 2 × 106 cells of each of the cell lines. For WT, DM and TM the results depict 4x each of lines 2 and 3, and 5 mice from line 1. MP and Y180F each represent 5 replicates of a single cell line. The box shows pairwise post-hoc Dunnet’s T3 p-values after one way ANOVA

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