Fig. 5From: Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivityFifteen poses (using Ledock poses) from the top 100 pharmaceutical agents listed in the data ordered by ComboPC score. Fourteen of these are actively-used pharmaceutical compounds and the last retains the potential to be active and is given because of its pharmaceutical activity towards cystic fibrosis, chronic obstructive pulmonary disease (COPD), and asthma. These are: a. Pirifibrate b. Cinacalcet c. Bendazol d. Phenyltoloxamine e. Triprolidine f. Alverine g. Benproperine h. and i. Tiaprofenic acid j. and k. Budralazine l. Cinacalcet m. Abacavir n. Oxaprozin o. TalniflumateBack to article page