Skip to main content

Table 2 Evaluation of the Drug-likeness of the compounds using Lipinski Rule of Five

From: Evaluation of selected carotenoids of Lycopersicon esculentum variants as therapeutic targets for ‘Alzheimer’s disease: an in silico approach

S/N

Compounds

Molecular Weight (Da)

Hydrogen bond donors

Hydrogen bond acceptors

milogP Values

Molar Refractivity

1

Neoxanthine

600,88

3

4

8.70

73.21

2

Violaxanthine

600.88

2

4

8.99

65.51

3

Betacarotene

536.89

0

0

9.84

40

4

Lutein

568.89

2

2

9.31

42

5

Donepezil

379.50

0

4

4.10

38.78