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Fig. 2 | BMC Molecular and Cell Biology

Fig. 2

From: Intercellular transfer of mitochondrial DNA carrying metastasis-enhancing pathogenic mutations from high- to low-metastatic tumor cells and stromal cells via extracellular vesicles

Fig. 2

Intercellular transfer of mitochondria-related vesicles derived from A11 cells to CAFs, macrophages and cytotoxic T cells. MTDR-labeled A11 cells (A11-MTDR) were cocultured with mtGFP-labeled WA-mFib cells (the inset shows α-SMA immunostaining), RAW264.7 cells or CTLL-2 cells for 24 h. The cells were observed under a laser confocal microscope. Arrows in the bottom row indicate CTLL-2 cells. Scale bars: 20 μm

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