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Fig. 6 | BMC Molecular and Cell Biology

Fig. 6

From: Induction of iPSC-derived Prg4-positive cells with characteristics of superficial zone chondrocytes and fibroblast-like synovial cells

Fig. 6

Transplantation of iPSC-derived Prg4-mRFP1-positive cells into SCID mice. Histological analysis of Achilles tendons and knee joints of SCID mice injected with either embryonic stem cell (ESC)-derived cells (control) or FACS-selected iPSC-derived Prg4-mRFP1-positive cells (#2–9). Semi-serial sections were stained with hematoxylin and eosin (H&E) and anti-RFP antibody (RFP). Middle panels of immunohistochemistry images are magnified from the squares in the corresponding upper panels (H&E staining). Lower panels of RFP immunofluorescent images are magnified from cell transplanted region of Achilles tendons and knee joints. Arrows point to mRFP1-positive cells. Asterisk indicates meniscus. Scale bars: 200 μm (upper panels),50 μm (middle panels) and 25 μm (lower panel)

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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