Fig. 2
Cyc affects the secretion of inflammatory factors and the synthesis of ECM on the IL-1β-induced C28/I2 cells. Cyc (10 μM) treated the IL-1β-induced C28/I2 cells. After incubating for 12 h, the total m6A level of each group were measured by dot blot analysis (A) and ELISA (B), the levels of inflammatory factors (IL-6, IL-8 and TNF-α) were measured by ELISA (C), the protein levels of collagen were examined by western blot (D and E)