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Fig. 1 | BMC Molecular and Cell Biology

Fig. 1

From: Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact

Fig. 1

 A) Tertiary structure of modeled CYP4F2 protein by I-TASSER web server in cartoon view. B) ProSA plot of quality assessment of CYP4F2 structure compared to proteins characterized experimentally. Data showed that CYP4F2 (shown in a black dot in the plot) is located in the region of the protein structure identified in the lab. C)Tertiary structure alignment of V433M (blue) and native (gray) form. A red surface color characterizes the position of the V433M variant. D) Close up view of structural alignment of native and mutant form. Data shows that methionine (red stick) has larger more buried side chain than valine (yellow stick)

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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